Evidence standard

A signal is a reason
to run a test.

Published findings are third-party evidence. They are not Antaeus Biosciences trial results. Human efficacy is unproven.

Read each source in context.

Different sources answer different questions. Historical human reports, animal experiments, and official surveillance serve distinct roles in the research case.

Historical human reports
Incomplete methods, allocation, or applicability limit interpretation. These reports justify a question, not a treatment claim.
Animal and exploratory findings
Animal findings, patent examples, and hypotheses require confirmation. They do not establish human efficacy.
Official context and process
Surveillance and authoritative guidance support the burden or development process. They do not demonstrate a bemitil benefit.

No source here establishes human efficacy for bemitil under controlled heat. Review every lead source and its limits.

Historical human reports

Human heat and exertion

1997 human heat/exertion reports (PMID 9162292, companion 9235216). Thermal tolerance and work capacity effects described; phenibut or its combination performed best; a bemitil-specific effect size is not available in the abstracts.

Historical occupational report

+13.7% static-effort endurance

1991 voyage paper: +13.7% static-effort endurance, 298 operators, 20-person detailed subset, allocation unspecified, not placebo-adjusted.

Book-reported human experiment

86.2% vs 68.1% of baseline

2019 monograph: 86.2% vs 68.1% of baseline dynamic-endurance retention in one bemitil arm vs placebo, 78 volunteers, no arm-specific n, no randomization procedure described, no controlled heat exposure.

Animal patent example

+50.5% running time in mice

RU2704126C2, Table 2: 41.66 vs 27.69 minutes running time in male mice at 40C, +50.5%, calculated from patent means. Small groups, inconsistent n reporting, requires independent replication.

Indirect animal mechanism

An RNA-dependent response

2002 rat study (PMID 12227091): RNA-dependent antioxidant response. Indirect, mechanism unresolved.

Official burden surveillance

518 heat-stroke cases

MSMR 2025: 518 heat-stroke and 2,233 heat-exhaustion cases in active-component service members; heat-stroke incidence up 6.9%, heat-exhaustion down 9.1%.

Investor materials